Sphingosine 1 Phosphate (S1P) Receptor 1 Is Decreased in Human Lung Microvascular Endothelial Cells of Smokers and Mediates S1P Effect on Autophagy

Destruction of alveoli by apoptosis induced by cigarette smoke (CS) is a major driver of emphysema pathogenesis. However, when compared to cells isolated from non-smokers, primary human lung microvascular endothelial cells (HLMVECs) isolated from chronic smokers are more resilient when exposed to ap...

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Detalles Bibliográficos
Autores principales: Goel, Khushboo, Beatman, Erica L., Egersdorf, Nicholas, Scruggs, April, Cao, Danting, Berdyshev, Evgeny V., Schweitzer, Kelly S., Petrache, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156252/
https://www.ncbi.nlm.nih.gov/pubmed/34068927
http://dx.doi.org/10.3390/cells10051200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156252/
https://www.ncbi.nlm.nih.gov/pubmed/34068927
http://dx.doi.org/10.3390/cells10051200

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