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Sphingosine 1 Phosphate (S1P) Receptor 1 Is Decreased in Human Lung Microvascular Endothelial Cells of Smokers and Mediates S1P Effect on Autophagy
Destruction of alveoli by apoptosis induced by cigarette smoke (CS) is a major driver of emphysema pathogenesis. However, when compared to cells isolated from non-smokers, primary human lung microvascular endothelial cells (HLMVECs) isolated from chronic smokers are more resilient when exposed to ap...
Autores principales: | Goel, Khushboo, Beatman, Erica L., Egersdorf, Nicholas, Scruggs, April, Cao, Danting, Berdyshev, Evgeny V., Schweitzer, Kelly S., Petrache, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156252/ https://www.ncbi.nlm.nih.gov/pubmed/34068927 http://dx.doi.org/10.3390/cells10051200 |
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