Amino Acid Substitutions in NS5 Contribute Differentially to Tembusu Virus Attenuation in Ducklings and Cell Cultures

Tembusu virus (TMUV), a highly infectious pathogenic flavivirus, causes severe egg-drop and encephalitis in domestic waterfowl, while the determinants responsible for viral pathogenicity are largely unknown. In our previous studies, virulent strain JXSP(2-4) had been completely attenuated by success...

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Detalles Bibliográficos
Autores principales: Sun, Xue, Sun, Mengxu, Zhang, Lijiao, Yu, Ziding, Li, Jinxin, Xie, Wanying, Su, Jingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156267/
https://www.ncbi.nlm.nih.gov/pubmed/34065634
http://dx.doi.org/10.3390/v13050921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156267/
https://www.ncbi.nlm.nih.gov/pubmed/34065634
http://dx.doi.org/10.3390/v13050921

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