Quercetin and Isorhamnetin Attenuate Benzo[a]pyrene-Induced Toxicity by Modulating Detoxification Enzymes through the AhR and NRF2 Signaling Pathways

Benzo[a]pyrene, classified as a Group 1 carcinogen, is metabolized to B[a]P-7,8-dihydrodiol-9,10-epoxide (BPDE), causing DNA mutations and eventually cancer. Quercetin is a dietary flavonoid abundant in fruits and vegetables. After quercetin intake, quercetin’s metabolites isorhamnetin and miquelian...

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Detalles Bibliográficos
Autores principales: Kim, Min, Jee, Seung-Cheol, Kim, Kyeong-Seok, Kim, Hyung-Sik, Yu, Kyoung-Nae, Sung, Jung-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156367/
https://www.ncbi.nlm.nih.gov/pubmed/34065697
http://dx.doi.org/10.3390/antiox10050787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156367/
https://www.ncbi.nlm.nih.gov/pubmed/34065697
http://dx.doi.org/10.3390/antiox10050787

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