Synthesis, Physicochemical Characteristics and Plausible Mechanism of Action of an Immunosuppressive Isoxazolo[5,4-e]-1,2,4-Triazepine Derivative (RM33)

Previous studies demonstrated strong anti-inflammatory properties of isoxazolo[5,4-e]-1,2,4-triazepine (RM33) in vivo. The aim of this investigation was to describe synthesis, determine physicochemical characteristics, evaluate biological activities in murine and human in vitro models, as well as to...

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Detalles Bibliográficos
Autores principales: Mączyński, Marcin, Regiec, Andrzej, Sochacka-Ćwikła, Aleksandra, Kochanowska, Iwona, Kocięba, Maja, Zaczyńska, Ewa, Artym, Jolanta, Kałas, Wojciech, Zimecki, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156388/
https://www.ncbi.nlm.nih.gov/pubmed/34063515
http://dx.doi.org/10.3390/ph14050468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156388/
https://www.ncbi.nlm.nih.gov/pubmed/34063515
http://dx.doi.org/10.3390/ph14050468

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