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Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration

Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there is an unmet need for biomarkers and assays to predict drug effect. It is well...

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Detalles Bibliográficos
Autores principales: Skovdahl, Helene Kolstad, Gopalakrishnan, Shreya, Svendsen, Tarjei Dahl, Granlund, Atle van Beelen, Bakke, Ingunn, Ginbot, Zekarias G., Thorsvik, Silje, Flatberg, Arnar, Sporsheim, Bjørnar, Ostrop, Jenny, Mollnes, Tom Eirik, Sandvik, Arne Kristian, Bruland, Torunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156408/
https://www.ncbi.nlm.nih.gov/pubmed/34054553
http://dx.doi.org/10.3389/fphar.2021.679741