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Sequence Neighborhoods Enable Reliable Prediction of Pathogenic Mutations in Cancer Genomes

SIMPLE SUMMARY: Cancer is caused by the accumulation of somatic mutations, some of which are responsible for the disease’s progression (drivers) while others are functionally neutral (passengers). Although several methods have been developed to distinguish between the two classes of mutations, very...

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Detalles Bibliográficos
Autores principales: Banerjee, Shayantan, Raman, Karthik, Ravindran, Balaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156421/
https://www.ncbi.nlm.nih.gov/pubmed/34068918
http://dx.doi.org/10.3390/cancers13102366