Afucosylated IgG Targets FcγRIV for Enhanced Tumor Therapy in Mice

SIMPLE SUMMARY: Cancer treatments are increasingly based on therapeutic antibodies to clear tumors. While in vivo mouse models are useful to predict effectiveness of human antibodies it is not completely clear how useful these models are to test antibodies engineered with enhanced effector functions...

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Detalles Bibliográficos
Autores principales: Braster, Rens, Bögels, Marijn, Benonisson, Hreinn, Wuhrer, Manfred, Plomp, Rosina, Bentlage, Arthur E. H., Korthouwer, Rianne, Visser, Remco, Verbeek, J. Sjef, van Egmond, Marjolein, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156657/
https://www.ncbi.nlm.nih.gov/pubmed/34069226
http://dx.doi.org/10.3390/cancers13102372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156657/
https://www.ncbi.nlm.nih.gov/pubmed/34069226
http://dx.doi.org/10.3390/cancers13102372

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