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Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/β-Catenin Signaling Inhibition

In colon cancer, wingless (Wnt)/β-catenin signaling is frequently upregulated; however, the creation of a molecular therapeutic agent targeting this pathway is still under investigation. This research aimed to study how nitazoxanide can affect Wnt/β-catenin signaling in colon cancer cells (HCT-116)...

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Detalles Bibliográficos
Autores principales: Abd El-Fadeal, Noha M., Nafie, Mohamed S., K. El-kherbetawy, Mohammed, El-mistekawy, Amr, Mohammad, Hala M. F., Elbahaie, Alaaeldeen M., Hashish, Abdullah A., Alomar, Suliman Y., Aloyouni, Sheka Yagub, El-dosoky, Mohamed, Morsy, Khaled M., Zaitone, Sawsan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156814/
https://www.ncbi.nlm.nih.gov/pubmed/34069111
http://dx.doi.org/10.3390/ijms22105213