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The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice

Our aim was to determine whether polyphosphazene (PCEP), Curdlan (β-glucan, a dectin-1 agonist), and Leptin could act as adjuvants to promote a Th17-type adaptive immune response in mice. Mice were vaccinated via the intramuscular route then boosted three weeks later with Ovalbumin plus: PCEP, Lepti...

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Detalles Bibliográficos
Autores principales: Chaffey, Alyssa, Hamonic, Glenn, Chand, Dylan, Mutwiri, George K., Wilson, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156850/
https://www.ncbi.nlm.nih.gov/pubmed/34069081
http://dx.doi.org/10.3390/vaccines9050507