Natural variants suppress mutations in hundreds of essential genes

The consequence of a mutation can be influenced by the context in which it operates. For example, loss of gene function may be tolerated in one genetic background, and lethal in another. The extent to which mutant phenotypes are malleable, the architecture of modifiers and the identities of causal g...

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Detalles Bibliográficos
Autores principales: Parts, Leopold, Batté, Amandine, Lopes, Maykel, Yuen, Michael W, Laver, Meredith, San Luis, Bryan‐Joseph, Yue, Jia‐Xing, Pons, Carles, Eray, Elise, Aloy, Patrick, Liti, Gianni, van Leeuwen, Jolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156963/
https://www.ncbi.nlm.nih.gov/pubmed/34042294
http://dx.doi.org/10.15252/msb.202010138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156963/
https://www.ncbi.nlm.nih.gov/pubmed/34042294
http://dx.doi.org/10.15252/msb.202010138

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