DNA Aptamers against Vaccinia-Related Kinase (VRK) 1 Block Proliferation in MCF7 Breast Cancer Cells

Vaccinia-related kinase (VRK) 1 is a serin/threonine kinase that plays an important role in DNA damage response (DDR), phosphorylating some proteins involved in this process such as 53BP1, NBS1 or H2AX, and in the cell cycle progression. In addition, VRK1 is overexpressed in many cancer types and it...

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Detalles Bibliográficos
Autores principales: Carrión-Marchante, Rebeca, Frezza, Valerio, Salgado-Figueroa, Ana, Pérez-Morgado, M. Isabel, Martín, M. Elena, González, Víctor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156982/
https://www.ncbi.nlm.nih.gov/pubmed/34067799
http://dx.doi.org/10.3390/ph14050473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156982/
https://www.ncbi.nlm.nih.gov/pubmed/34067799
http://dx.doi.org/10.3390/ph14050473

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