Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)

Recent work has shown that bilirubin has a hormonal function by binding to the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that drives the transcription of genes to control adiposity. Our previous in silico work predicted three potential amino acids that bilirubin may in...

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Detalles Bibliográficos
Autores principales: Gordon, Darren M., Hong, Stephen H., Kipp, Zachary A., Hinds, Terry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157031/
https://www.ncbi.nlm.nih.gov/pubmed/34067839
http://dx.doi.org/10.3390/molecules26102975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157031/
https://www.ncbi.nlm.nih.gov/pubmed/34067839
http://dx.doi.org/10.3390/molecules26102975

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