Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation

The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low oral bioavailability and extensive first pass metabolism. The purpose of this investigation was to optimize the thin mucoadhesive buccal film of rizatriptan and assess the practicability of its development...

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Detalles Bibliográficos
Autores principales: Nair, Anroop B., Shah, Jigar, Jacob, Shery, Al-Dhubiab, Bandar E., Patel, Vimal, Sreeharsha, Nagaraja, Shinu, Pottathil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157038/
https://www.ncbi.nlm.nih.gov/pubmed/34063402
http://dx.doi.org/10.3390/pharmaceutics13050728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157038/
https://www.ncbi.nlm.nih.gov/pubmed/34063402
http://dx.doi.org/10.3390/pharmaceutics13050728

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