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Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis

SIMPLE SUMMARY: The nucleus is the largest and stiffest organelle of tumor cells. Cancer metastasis depends on the ability of cancer cells circulating in the blood to exit blood vessels and survive in target organs. The roles of the shell (lamina) of the nucleus in cancer cell migration and survival...

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Detalles Bibliográficos
Autores principales: Roncato, Francesco, Regev, Ofer, Feigelson, Sara W., Yadav, Sandeep Kumar, Kaczmarczyk, Lukasz, Levi, Nehora, Drago-Garcia, Diana, Ovadia, Samuel, Kizner, Marina, Addadi, Yoseph, Sabino, João C., Ovadya, Yossi, de Almeida, Sérgio F., Feldmesser, Ester, Gerlitz, Gabi, Alon, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157058/
https://www.ncbi.nlm.nih.gov/pubmed/34069191
http://dx.doi.org/10.3390/cancers13102383