Inhibition of Lysine 63 Ubiquitination Prevents the Progression of Renal Fibrosis in Diabetic DBA/2J Mice

Diabetic nephropathy (DN) is the most frequent cause of end-stage renal disease. Tubulointerstitial accumulation of lysine 63 (K63)-ubiquitinated (Ub) proteins is involved in the progression of DN fibrosis and correlates with urinary miR-27b-3p downregulation. We explored the renoprotective effect o...

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Detalles Bibliográficos
Autores principales: Pontrelli, Paola, Conserva, Francesca, Menghini, Rossella, Rossini, Michele, Stasi, Alessandra, Divella, Chiara, Casagrande, Viviana, Cinefra, Claudia, Barozzino, Mariagrazia, Simone, Simona, Pesce, Francesco, Castellano, Giuseppe, Stallone, Giovanni, Gallone, Anna, Giorgino, Francesco, Federici, Massimo, Gesualdo, Loreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157080/
https://www.ncbi.nlm.nih.gov/pubmed/34068941
http://dx.doi.org/10.3390/ijms22105194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157080/
https://www.ncbi.nlm.nih.gov/pubmed/34068941
http://dx.doi.org/10.3390/ijms22105194

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