Cargando…
Inhibition of Lysine 63 Ubiquitination Prevents the Progression of Renal Fibrosis in Diabetic DBA/2J Mice
Diabetic nephropathy (DN) is the most frequent cause of end-stage renal disease. Tubulointerstitial accumulation of lysine 63 (K63)-ubiquitinated (Ub) proteins is involved in the progression of DN fibrosis and correlates with urinary miR-27b-3p downregulation. We explored the renoprotective effect o...
Autores principales: | Pontrelli, Paola, Conserva, Francesca, Menghini, Rossella, Rossini, Michele, Stasi, Alessandra, Divella, Chiara, Casagrande, Viviana, Cinefra, Claudia, Barozzino, Mariagrazia, Simone, Simona, Pesce, Francesco, Castellano, Giuseppe, Stallone, Giovanni, Gallone, Anna, Giorgino, Francesco, Federici, Massimo, Gesualdo, Loreto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157080/ https://www.ncbi.nlm.nih.gov/pubmed/34068941 http://dx.doi.org/10.3390/ijms22105194 |
Ejemplares similares
-
Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy
por: Conserva, Francesca, et al.
Publicado: (2019) -
Pre-Transplant Expression of CCR-2 in Kidney Transplant Recipients Is Associated With the Development of Delayed Graft Function
por: Pontrelli, Paola, et al.
Publicado: (2022) -
Acute Kidney Injury in Kidney Transplant Patients in Intensive Care Unit: From Pathogenesis to Clinical Management
por: Fiorentino, Marco, et al.
Publicado: (2023) -
Recent advances in molecular mechanisms of acute kidney injury in patients with diabetes mellitus
por: Infante, Barbara, et al.
Publicado: (2023) -
Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling
por: Castellano, Giuseppe, et al.
Publicado: (2018)