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The Individual Effects of Cyclin-Dependent Kinase Inhibitors on Head and Neck Cancer Cells—A Systematic Analysis

SIMPLE SUMMARY: This study examined the therapeutic potential of a combined therapy approach, based on clinical approved drugs (5-FU, Cisplatin, cetuximab) and cyclin-dependent kinase inhibitors (CDKi, dinaciclib, palbociclib, THZ1). We identified individual effects on head and neck squamous cell ca...

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Detalles Bibliográficos
Autores principales: Schoenwaelder, Nina, Salewski, Inken, Engel, Nadja, Krause, Mareike, Schneider, Björn, Müller, Michael, Riess, Christin, Lemcke, Heiko, Skorska, Anna, Grosse-Thie, Christina, Junghanss, Christian, Maletzki, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157193/
https://www.ncbi.nlm.nih.gov/pubmed/34063457
http://dx.doi.org/10.3390/cancers13102396