Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, mainly characterized by motor deficits correlated with progressive dopaminergic neuronal loss in the substantia nigra pars compacta (SN). Necroptosis is a caspase-independent form of regulated cell death mediated by the c...

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Detalles Bibliográficos
Autores principales: Oliveira, Sara R., Dionísio, Pedro A., Gaspar, Maria M., Ferreira, Maria B. T., Rodrigues, Catarina A. B., Pereira, Rita G., Estevão, Mónica S., Perry, Maria J., Moreira, Rui, Afonso, Carlos A. M., Amaral, Joana D., Rodrigues, Cecília M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157267/
https://www.ncbi.nlm.nih.gov/pubmed/34069782
http://dx.doi.org/10.3390/ijms22105289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157267/
https://www.ncbi.nlm.nih.gov/pubmed/34069782
http://dx.doi.org/10.3390/ijms22105289

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