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Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, mainly characterized by motor deficits correlated with progressive dopaminergic neuronal loss in the substantia nigra pars compacta (SN). Necroptosis is a caspase-independent form of regulated cell death mediated by the c...
Autores principales: | Oliveira, Sara R., Dionísio, Pedro A., Gaspar, Maria M., Ferreira, Maria B. T., Rodrigues, Catarina A. B., Pereira, Rita G., Estevão, Mónica S., Perry, Maria J., Moreira, Rui, Afonso, Carlos A. M., Amaral, Joana D., Rodrigues, Cecília M. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157267/ https://www.ncbi.nlm.nih.gov/pubmed/34069782 http://dx.doi.org/10.3390/ijms22105289 |
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