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Combination of chemotherapy and oxidative stress to enhance cancer cell apoptosis

Cancer cells are vulnerable to reactive oxygen species (ROS) due to their abnormal redox environment. Accordingly, combination of chemotherapy and oxidative stress has gained increasing interest for the treatment of cancer. We report a novel seleno-prodrug of gemcitabine (Gem), Se–Gem, and evaluated...

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Detalles Bibliográficos
Autores principales: Li, Xinming, Hou, Yanan, Zhao, Jintao, Li, Jin, Wang, Song, Fang, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157308/
https://www.ncbi.nlm.nih.gov/pubmed/34122827
http://dx.doi.org/10.1039/c9sc05997k