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Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFκB/Caspase-1/IL-1β Pathway

Human gingival mesenchymal stem cells (hGMSCs) and endothelial committed hGMSCs (e-hGMSCs) have considerable potential to serve as an in vitro model to replicate the inflammation sustained by Porphyromonas gingivalis in periodontal and cardiovascular diseases. The present study aimed to investigate...

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Detalles Bibliográficos
Autores principales: Pizzicannella, Jacopo, Fonticoli, Luigia, Guarnieri, Simone, Marconi, Guya D., Rajan, Thangavelu Soundara, Trubiani, Oriana, Diomede, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157377/
https://www.ncbi.nlm.nih.gov/pubmed/34069836
http://dx.doi.org/10.3390/antiox10050797