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MH-76, a Novel Non-Quinazoline α(1)-Adrenoceptor Antagonist, but Not Prazosin Reduces Inflammation and Improves Insulin Signaling in Adipose Tissue of Fructose-Fed Rats

Background: Quinazoline α(1)-adrenoceptors antagonists have been shown to exert moderately favorable effects on the metabolic profile in hypertensive patients. However, based on AntiHypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, they are no longer recommend...

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Detalles Bibliográficos
Autores principales: Kubacka, Monika, Mogilski, Szczepan, Zadrożna, Monika, Nowak, Barbara, Szafarz, Małgorzata, Pomierny, Bartosz, Marona, Henryk, Waszkielewicz, Anna, Jawień, Wojciech, Sapa, Jacek, Bednarski, Marek, Knutelska, Joanna, Kotańska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157569/
https://www.ncbi.nlm.nih.gov/pubmed/34069933
http://dx.doi.org/10.3390/ph14050477