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Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure

Commercial topical ocular formulations for hydrophobic actives rely on the use of suspensions or oil in water emulsions and neither of these formulation modalities adequately promote drug penetration into ocular tissues. Using the ocular relevant hydrophobic drug, cyclosporine A (CsA), a non-irritan...

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Detalles Bibliográficos
Autores principales: Uchegbu, Ijeoma F., Breznikar, Jan, Zaffalon, Alessandra, Odunze, Uche, Schätzlein, Andreas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157576/
https://www.ncbi.nlm.nih.gov/pubmed/34069936
http://dx.doi.org/10.3390/pharmaceutics13050744