Tests of association based on genomic windows can lead to spurious associations when using genotype panels with heterogeneous SNP densities

Dense single nucleotide polymorphism (SNP) panels are widely used for genome-wide association studies (GWAS). In these panels, SNPs within a genomic segment tend to be highly correlated. Thus, association studies based on testing the significance of single SNPs are not very effective, and genomic-wi...

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Detalles Bibliográficos
Autores principales: Li, Jinghui, Wang, Zigui, Fernando, Rohan, Cheng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157676/
https://www.ncbi.nlm.nih.gov/pubmed/34039266
http://dx.doi.org/10.1186/s12711-021-00638-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157676/
https://www.ncbi.nlm.nih.gov/pubmed/34039266
http://dx.doi.org/10.1186/s12711-021-00638-x

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