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Semaphorin3A increases M1-like microglia and retinal ganglion cell apoptosis after optic nerve injury

BACKGROUND: The mechanisms leading to retinal ganglion cell (RGC) death after optic nerve injury have not been fully elucidated. Current evidence indicates that microglial activation and M1- and M2-like dynamics may be an important factor in RGC apoptosis after optic nerve crush (ONC). Semaphorin3A...

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Detalles Bibliográficos
Autores principales: Yun-Jia, Liu, Xi, Chen, Jie-Qiong, Zhang, Jing-Yi, Zhu, Sen, Lin, Jian, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157735/
https://www.ncbi.nlm.nih.gov/pubmed/34039431
http://dx.doi.org/10.1186/s13578-021-00603-7