3-Bromotetrazine: labelling of macromolecules via monosubstituted bifunctional s-tetrazines

We report the synthesis and first characterisation of the novel chemical probe 3-bromotetrazine and establish its reactivity towards nucleophiles. This led to the synthesis of several novel classes of 3-monosubstituted s-tetrazines. A remarkable functional group selectivity is observed and is utilis...

Descripción completa

Detalles Bibliográficos
Autores principales: Schnell, Simon D., Hoff, Lukas V., Panchagnula, Advaita, Wurzenberger, Maximilian H. H., Klapötke, Thomas M., Sieber, Simon, Linden, Anthony, Gademann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157750/
https://www.ncbi.nlm.nih.gov/pubmed/34122808
http://dx.doi.org/10.1039/c9sc06169j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157750/
https://www.ncbi.nlm.nih.gov/pubmed/34122808
http://dx.doi.org/10.1039/c9sc06169j

Ejemplares similares