Cargando…

Hyperoxia causes senescence and increases glycolysis in cultured lung epithelial cells

Supplemental oxygen and mechanical ventilation commonly used in premature infants may lead to chronic lung disease of prematurity, which is characterized by arrested alveolar development and dysmorphic vascular development. Hyperoxia is also known to dysregulate p53, senescence, and metabolism. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scaffa, Alejandro M., Peterson, Abigail L., Carr, Jennifer F., Garcia, David, Yao, Hongwei, Dennery, Phyllis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157762/ https://www.ncbi.nlm.nih.gov/pubmed/34042288 http://dx.doi.org/10.14814/phy2.14839

Ejemplares similares

Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice
por: Garcia, David, et al.
Publicado: (2020)

Heme Oxygenase-1 Supports Mitochondrial Energy Production and Electron Transport Chain Activity in Cultured Lung Epithelial Cells
por: Carr, Jennifer F., et al.
Publicado: (2020)

Involvement of miRNA-34a regulated Krüppel-like factor 4 expression in hyperoxia-induced senescence in lung epithelial cells
por: Maeda, Hajime, et al.
Publicado: (2022)

Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice
por: Peterson, Abigail L., et al.
Publicado: (2020)

Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury
por: Chang, Jason L., et al.
Publicado: (2022)

The pentose phosphate pathway mediates hyperoxia-induced lung vascular dysgenesis and alveolar simplification in neonates
por: Gong, Jiannan, et al.
Publicado: (2021)

Timing and cell specificity of senescence drives postnatal lung development and injury
por: Yao, Hongwei, et al.
Publicado: (2023)

Single-cell transcriptomics reveals lasting changes in the lung cellular landscape into adulthood after neonatal hyperoxic exposure
por: Scaffa, Alejandro, et al.
Publicado: (2021)

Identification of Heme Oxygenase-1 as a Putative DNA-Binding Protein
por: Scaffa, Alejandro, et al.
Publicado: (2022)

Heme Oxygenase 1 and 2 Differentially Regulate Glucose Metabolism and Adipose Tissue Mitochondrial Respiration: Implications for Metabolic Dysregulation
por: Yao, Hongwei, et al.
Publicado: (2020)

Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of β-catenin/hnRNPK signaling()
por: Yang, Guang, et al.
Publicado: (2013)

Loss of the transcriptional repressor Rev-erbα upregulates metabolism and proliferation in cultured mouse embryonic fibroblasts
por: Gillis, Sean P., et al.
Publicado: (2021)

Metabolic dysregulation in bronchopulmonary dysplasia: Implications for identification of biomarkers and therapeutic approaches
por: Yue, Li, et al.
Publicado: (2021)

Diminished Resistance to Hyperoxia in Brains of Reproductively Senescent Female CBA/H Mice
por: Šarić, Ana, et al.
Publicado: (2015)

Evaluating the Beneficial and Detrimental Effects of Bile Pigments in Early and Later Life
por: Dennery, Phyllis A.
Publicado: (2012)

Lung epithelial‐specific TRIP‐1 overexpression maintains epithelial integrity during hyperoxia exposure
por: Nyp, Michael F., et al.
Publicado: (2018)

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
por: Hariton, Florence, et al.
Publicado: (2018)

Regulation of ACE-2 enzyme by hyperoxia in lung epithelial cells by post-translational modification
por: Mohamed, Tarek, et al.
Publicado: (2021)

BMI1 Silencing Induces Mitochondrial Dysfunction in Lung Epithelial Cells Exposed to Hyperoxia
por: Hernández-Cuervo, Helena, et al.
Publicado: (2022)

Neuroprotection Caused by Hyperoxia Preconditioning in Animal Stroke Models
por: Bigdeli, Mohammad Reza
Publicado: (2011)

Does UCP2 Couple Hyperoxia to Lung Injury?
por: Larson-Casey, Jennifer L., et al.
Publicado: (2021)

Dangers of hyperoxia
por: Singer, Mervyn, et al.
Publicado: (2021)

Hyperoxia in depression
por: Belmaker, R., et al.
Publicado: (2021)

Flotillin-2 Modulates Fas Signaling Mediated Apoptosis after Hyperoxia in Lung Epithelial Cells
por: Wei, Shuquan, et al.
Publicado: (2013)

Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung
por: Mach, William J., et al.
Publicado: (2011)

Cellular Senescence in the Lung: The Central Role of Senescent Epithelial Cells
por: Hansel, Christine, et al.
Publicado: (2020)

Oxygen Variations—Insights into Hypoxia, Hyperoxia and Hyperbaric Hyperoxia—Is the Dose the Clue?
por: Balestra, Costantino, et al.
Publicado: (2023)

Hyperoxia increases interleukin-17 in airway epithelial cells, alveolar type II cells and alveolar macrophages after ovalbumin-induced lung inflammation
por: Aarestrup, Fernando Monteiro, et al.
Publicado: (2015)

Effects of xenon gas on human airway epithelial cells during hyperoxia and hypothermia
por: Zhu, Y., et al.
Publicado: (2020)

Disrupted postnatal lung development in heme oxygenase-1 deficient mice
por: Zhuang, Tiangang, et al.
Publicado: (2010)

Hyperoxia Induced Hypomyelination
por: Song, Weilin, et al.
Publicado: (2022)

Oxygen injury in neonates: which is worse? hyperoxia, hypoxia, or alternating hyperoxia/hypoxia
por: Mohamed, Tarek, et al.
Publicado: (2020)

Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed
por: Eshmuminov, Dilmurodjon, et al.
Publicado: (2020)

Expression and function of aquaporin-1 in hyperoxia-exposed alveolar epithelial type II cells
por: ZHANG, QIU-YUE, et al.
Publicado: (2014)

Contrasting effects of hyperoxia on GM-CSF gene transcription in alveolar epithelial cells and T cells
por: Sturrock, Anne, et al.
Publicado: (2015)

Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation
por: Riccetti, Matthew R., et al.
Publicado: (2022)

Different culture media modulate growth, heterogeneity, and senescence in human mammary epithelial cell cultures
por: Lee, Jonathan K., et al.
Publicado: (2018)

Hyperoxia after cardiac arrest may not increase ischemia-reperfusion injury
por: Hoedemaekers, Cornelia W, et al.
Publicado: (2011)

Hyperoxia results in increased aerobic metabolism following acute brain injury
por: Ghosh, Arnab, et al.
Publicado: (2016)

The NRF2 Activation and Antioxidative Response Are Not Impaired Overall during Hyperoxia-Induced Lung Epithelial Cell Death
por: Potteti, Haranatha R., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_gfib1riesmsdtrtn2pbof9kh8i