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Effect of Vitamin K-Mediated PXR Activation on Drug-Metabolizing Gene Expression in Human Intestinal Carcinoma LS180 Cell Line

The pregnane X receptor (PXR) is the key regulator of our defense mechanism against foreign substances such as drugs, dietary nutrients, or environmental pollutants. Because of increased health consciousness, the use of dietary supplements has gradually increased, and most of them can activate PXR....

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Detalles Bibliográficos
Autores principales: Sultana, Halima, Kato, Ayaka, Ohashi, Ai, Takashima, Rie, Katsurai, Tomoko, Sato, Shoko, Monma, Masafumi, Ohsaki, Yusuke, Goto, Tomoko, Komai, Michio, Shirakawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157877/
https://www.ncbi.nlm.nih.gov/pubmed/34069974
http://dx.doi.org/10.3390/nu13051709