Soluble immune checkpoints and T-cell subsets in blood as biomarkers for resistance to immunotherapy in melanoma patients

Different mechanisms lead to immune checkpoint inhibitor (ICI) resistance. Identifying clinically useful biomarkers might improve drug selection and patients’ therapy. We analyzed the soluble immune checkpoints sPD1, sPDL1, sLAG3, and sTIM3 using ELISA and their expression on circulating T cells usi...

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Detalles Bibliográficos
Autores principales: Machiraju, Devayani, Wiecken, Melanie, Lang, Nina, Hülsmeyer, Ingrid, Roth, Jasmin, Schank, Timo E., Eurich, Rosa, Halama, Niels, Enk, Alexander, Hassel, Jessica C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158029/
https://www.ncbi.nlm.nih.gov/pubmed/34104542
http://dx.doi.org/10.1080/2162402X.2021.1926762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158029/
https://www.ncbi.nlm.nih.gov/pubmed/34104542
http://dx.doi.org/10.1080/2162402X.2021.1926762

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