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Direct Visualization of Amlodipine Intervention into Living Cells by Means of Fluorescence Microscopy

Amlodipine, a unique long-lasting calcium channel antagonist and antihypertensive drug, has weak fluorescence in aqueous solutions. In the current paper, we show that direct visualization of amlodipine in live cells is possible due to the enhanced emission in cellular environment. We examined the im...

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Detalles Bibliográficos
Autores principales: Quentin, Christine, Gerasimaitė, Rūta, Freidzon, Alexandra, Atabekyan, Levon S., Lukinavičius, Gražvydas, Belov, Vladimir N., Mitronova, Gyuzel Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158129/
https://www.ncbi.nlm.nih.gov/pubmed/34070063
http://dx.doi.org/10.3390/molecules26102997