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Prediction and Evolution of the Molecular Fitness of SARS-CoV-2 Variants: Introducing SpikePro

The understanding of the molecular mechanisms driving the fitness of the SARS-CoV-2 virus and its mutational evolution is still a critical issue. We built a simplified computational model, called SpikePro, to predict the SARS-CoV-2 fitness from the amino acid sequence and structure of the spike prot...

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Detalles Bibliográficos
Autores principales: Pucci, Fabrizio, Rooman, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158131/
https://www.ncbi.nlm.nih.gov/pubmed/34070055
http://dx.doi.org/10.3390/v13050935