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Thymoquinone-entrapped chitosan-modified nanoparticles: formulation optimization to preclinical bioavailability assessments

The major limitation with the oral administration of most of the phytochemicals is their low aqueous solubility and bioavailability. Thymoquinone (THQ) is one of the most widely used phytochemicals used to treat a variety of diseases. However, strong lipophilic characteristics limit its clinical app...

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Detalles Bibliográficos
Autores principales: Rahat, Iqra, Imam, Syed Sarim, Rizwanullah, Md., Alshehri, Sultan, Asif, Mohammad, Kala, Chandra, Taleuzzaman, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158209/
https://www.ncbi.nlm.nih.gov/pubmed/34036860
http://dx.doi.org/10.1080/10717544.2021.1927245