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Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages

Herpes simplex virus 1 (HSV-1) infects the cornea and caused blinding ocular disease. In the present study, we evaluated whether and how a novel engineered version of fibroblast growth factor-1 (FGF-1), designated as TTHX1114, would reduce the severity of HSV-1-induced and recurrent ocular herpes in...

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Detalles Bibliográficos
Autores principales: Dhanushkodi, Nisha R., Srivastava, Ruchi, Coulon, Pierre-Gregoire A., Prakash, Swayam, Roy, Soumyabrata, Bagnol, Didier, David, Eveleth D., BenMohamed, Lbachir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158292/
https://www.ncbi.nlm.nih.gov/pubmed/34054858
http://dx.doi.org/10.3389/fimmu.2021.673763