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Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages
Herpes simplex virus 1 (HSV-1) infects the cornea and caused blinding ocular disease. In the present study, we evaluated whether and how a novel engineered version of fibroblast growth factor-1 (FGF-1), designated as TTHX1114, would reduce the severity of HSV-1-induced and recurrent ocular herpes in...
Autores principales: | Dhanushkodi, Nisha R., Srivastava, Ruchi, Coulon, Pierre-Gregoire A., Prakash, Swayam, Roy, Soumyabrata, Bagnol, Didier, David, Eveleth D., BenMohamed, Lbachir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158292/ https://www.ncbi.nlm.nih.gov/pubmed/34054858 http://dx.doi.org/10.3389/fimmu.2021.673763 |
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