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CX-4945 and siRNA-Mediated Knockdown of CK2 Improves Cisplatin Response in HPV(+) and HPV(−) HNSCC Cell Lines

Head and neck squamous cell carcinoma (HNSCC) can be categorized into human papillomavirus (HPV) positive or negative disease. Elevated protein kinase CK2 level and activity have been historically observed in HNSCC cells. Previous studies on CK2 in HNSCC did not generally include consideration of HP...

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Detalles Bibliográficos
Autores principales: Trembley, Janeen H., Li, Bin, Kren, Betsy T., Gravely, Amy A., Caicedo-Granados, Emiro, Klein, Mark A., Ahmed, Khalil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158385/
https://www.ncbi.nlm.nih.gov/pubmed/34070147
http://dx.doi.org/10.3390/biomedicines9050571