Cephalotaxine Inhibits the Survival of Leukemia Cells by Activating Mitochondrial Apoptosis Pathway and Inhibiting Autophagy Flow

Cephalotaxine (CET) is a natural alkaloid with potent antileukemia effects. However, its underlying molecular mechanism has not been well understood. In this study, we verified that CET significantly inhibited the viability of various leukemia cells, including HL-60, NB4, Jurkat, K562, Raji and MOLT...

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Detalles Bibliográficos
Autores principales: Liu, Tingting, Guo, Qiang, Zheng, Shuze, Liu, Yang, Yang, Heng, Zhao, Meimei, Yao, Lu, Zeng, Kewu, Tu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158396/
https://www.ncbi.nlm.nih.gov/pubmed/34070111
http://dx.doi.org/10.3390/molecules26102996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158396/
https://www.ncbi.nlm.nih.gov/pubmed/34070111
http://dx.doi.org/10.3390/molecules26102996

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