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Cephalotaxine Inhibits the Survival of Leukemia Cells by Activating Mitochondrial Apoptosis Pathway and Inhibiting Autophagy Flow
Cephalotaxine (CET) is a natural alkaloid with potent antileukemia effects. However, its underlying molecular mechanism has not been well understood. In this study, we verified that CET significantly inhibited the viability of various leukemia cells, including HL-60, NB4, Jurkat, K562, Raji and MOLT...
Autores principales: | Liu, Tingting, Guo, Qiang, Zheng, Shuze, Liu, Yang, Yang, Heng, Zhao, Meimei, Yao, Lu, Zeng, Kewu, Tu, Pengfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158396/ https://www.ncbi.nlm.nih.gov/pubmed/34070111 http://dx.doi.org/10.3390/molecules26102996 |
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