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A Hybrid In Silico and Tumor-on-a-Chip Approach to Model Targeted Protein Behavior in 3D Microenvironments

SIMPLE SUMMARY: Engineered proteins possess a great therapeutic potential, but the development of such therapies is impeded during preclinical studies by the lack of in vitro models that accurately simulate the human physiology. Animal models, on the other hand, also have difficulties predicting hum...

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Detalles Bibliográficos
Autores principales: Palacio-Castañeda, Valentina, Dumas, Simon, Albrecht, Philipp, Wijgers, Thijmen J., Descroix, Stéphanie, Verdurmen, Wouter P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158470/
https://www.ncbi.nlm.nih.gov/pubmed/34070171
http://dx.doi.org/10.3390/cancers13102461