The Role of ZEB2 in Human CD8 T Lymphocytes: Clinical and Cellular Immune Profiling in Mowat–Wilson Syndrome

The Zeb2 gene encodes a transcription factor (ZEB2) that acts as an important immune mediator in mice, where it is expressed in early-activated effector CD8 T cells, and limits effector differentiation. Zeb2 homozygous knockout mice have deficits in CD8 T cells and NK cells. Mowat–Wilson syndrome (M...

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Detalles Bibliográficos
Autores principales: Frith, Katie, Munier, C. Mee Ling, Hastings, Lucy, Mowat, David, Wilson, Meredith, Seddiki, Nabila, Macintosh, Rebecca, Kelleher, Anthony D., Gray, Paul, Zaunders, John James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158478/
https://www.ncbi.nlm.nih.gov/pubmed/34070208
http://dx.doi.org/10.3390/ijms22105324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158478/
https://www.ncbi.nlm.nih.gov/pubmed/34070208
http://dx.doi.org/10.3390/ijms22105324

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