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The Role of ZEB2 in Human CD8 T Lymphocytes: Clinical and Cellular Immune Profiling in Mowat–Wilson Syndrome

The Zeb2 gene encodes a transcription factor (ZEB2) that acts as an important immune mediator in mice, where it is expressed in early-activated effector CD8 T cells, and limits effector differentiation. Zeb2 homozygous knockout mice have deficits in CD8 T cells and NK cells. Mowat–Wilson syndrome (M...

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Detalles Bibliográficos
Autores principales:	Frith, Katie, Munier, C. Mee Ling, Hastings, Lucy, Mowat, David, Wilson, Meredith, Seddiki, Nabila, Macintosh, Rebecca, Kelleher, Anthony D., Gray, Paul, Zaunders, John James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158478/ https://www.ncbi.nlm.nih.gov/pubmed/34070208 http://dx.doi.org/10.3390/ijms22105324

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