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Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice

The WWC protein family is an upstream regulator of the Hippo signalling pathway that is involved in many cellular processes. We examined the effect of an endothelium-specific WWC1 and/or WWC2 knock-out on ocular angiogenesis. Knock-outs were induced in C57BL/6 mice at the age of one day (P1) and eva...

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Detalles Bibliográficos
Autores principales: Brücher, Viktoria Constanze, Egbring, Charlotte, Plagemann, Tanja, Nedvetsky, Pavel I., Höffken, Verena, Pavenstädt, Hermann, Eter, Nicole, Kremerskothen, Joachim, Heiduschka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158494/
https://www.ncbi.nlm.nih.gov/pubmed/34070186
http://dx.doi.org/10.3390/ijms22105321