Untangling Dual-Targeting Therapeutic Mechanism of Epidermal Growth Factor Receptor (EGFR) Based on Reversed Allosteric Communication

Dual-targeting therapeutics by coadministration of allosteric and orthosteric drugs is drawing increased attention as a revolutionary strategy for overcoming the drug-resistance problems. It was further observed that the occupation of orthosteric sites by therapeutics agents has the potential to enh...

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Detalles Bibliográficos
Autores principales: Qiu, Yuran, Yin, Xiaolan, Li, Xinyi, Wang, Yuanhao, Fu, Qiang, Huang, Renhua, Lu, Shaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158526/
https://www.ncbi.nlm.nih.gov/pubmed/34070173
http://dx.doi.org/10.3390/pharmaceutics13050747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158526/
https://www.ncbi.nlm.nih.gov/pubmed/34070173
http://dx.doi.org/10.3390/pharmaceutics13050747

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