Real-World Use of Azathioprine Metabolites Changes Clinical Management of Inflammatory Bowel Disease

BACKGROUND: Thiopurines such as 6-mercaptopurine and azathioprine have complex metabolism, resulting in significant inter-individual differences in clinical efficacy and risk of drug toxicity, making conventional weight-based dosing inaccurate and potentially unsafe. Therapeutic drug monitoring (TDM...

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Detalles Bibliográficos
Autores principales: Wilson, Laura, Tuson, Stephanie, Yang, Lufang, Loomes, Dustin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158651/
https://www.ncbi.nlm.nih.gov/pubmed/34056527
http://dx.doi.org/10.1093/jcag/gwaa005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158651/
https://www.ncbi.nlm.nih.gov/pubmed/34056527
http://dx.doi.org/10.1093/jcag/gwaa005

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