Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis

Ulcerative colitis (UC), a severe chronic disease with unclear etiology that is associated with increased risk for colorectal cancer, is accompanied by dysregulation of cytokines. Epstein–Barr virus-induced gene 3 (EBI3) encodes a subunit in the unique heterodimeric IL-12 cytokine family of either p...

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Detalles Bibliográficos
Autores principales: Wetzel, Alexandra, Scholtka, Bettina, Schumacher, Fabian, Rawel, Harshadrai, Geisendörfer, Birte, Kleuser, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158689/
https://www.ncbi.nlm.nih.gov/pubmed/34069352
http://dx.doi.org/10.3390/ijms22105329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158689/
https://www.ncbi.nlm.nih.gov/pubmed/34069352
http://dx.doi.org/10.3390/ijms22105329

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