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Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis

Ulcerative colitis (UC), a severe chronic disease with unclear etiology that is associated with increased risk for colorectal cancer, is accompanied by dysregulation of cytokines. Epstein–Barr virus-induced gene 3 (EBI3) encodes a subunit in the unique heterodimeric IL-12 cytokine family of either p...

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Detalles Bibliográficos
Autores principales:	Wetzel, Alexandra, Scholtka, Bettina, Schumacher, Fabian, Rawel, Harshadrai, Geisendörfer, Birte, Kleuser, Burkhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158689/ https://www.ncbi.nlm.nih.gov/pubmed/34069352 http://dx.doi.org/10.3390/ijms22105329

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