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Characterization of the CYP3A4 Enzyme Inhibition Potential of Selected Flavonoids

Acacetin, apigenin, chrysin, and pinocembrin are flavonoid aglycones found in foods such as parsley, honey, celery, and chamomile tea. Flavonoids can act as substrates and inhibitors of the CYP3A4 enzyme, a heme containing enzyme responsible for the metabolism of one third of drugs on the market. Th...

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Detalles Bibliográficos
Autores principales: Kondža, Martin, Bojić, Mirza, Tomić, Ivona, Maleš, Željan, Rezić, Valentina, Ćavar, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158701/
https://www.ncbi.nlm.nih.gov/pubmed/34069400
http://dx.doi.org/10.3390/molecules26103018