17-AAG-Induced Activation of the Autophagic Pathway in Leishmania Is Associated with Parasite Death

The heat shock protein 90 (Hsp90) is thought to be an excellent drug target against parasitic diseases. The leishmanicidal effect of an Hsp90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin (17-AAG), was previously demonstrated in both in vitro and in vivo models of cutaneous leishmaniasis. Para...

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Detalles Bibliográficos
Autores principales: Petersen, Antonio Luis de O. A., Cull, Benjamin, Dias, Beatriz R. S., Palma, Luana C., Luz, Yasmin da S., de Menezes, Juliana P. B., Mottram, Jeremy C., Veras, Patrícia S. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158731/
https://www.ncbi.nlm.nih.gov/pubmed/34069389
http://dx.doi.org/10.3390/microorganisms9051089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158731/
https://www.ncbi.nlm.nih.gov/pubmed/34069389
http://dx.doi.org/10.3390/microorganisms9051089

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