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Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors

Recombinant adeno-associated virus (rAAV) vectors have evolved as one of the most promising technologies for gene therapy due to their good safety profile, high transduction efficacy, and long-term gene expression in nondividing cells. rAAV-based gene therapy holds great promise for treating genetic...

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Detalles Bibliográficos
Autores principales: Rieser, Ruth, Koch, Johanna, Faccioli, Greta, Richter, Klaus, Menzen, Tim, Biel, Martin, Winter, Gerhard, Michalakis, Stylianos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158740/
https://www.ncbi.nlm.nih.gov/pubmed/34070226
http://dx.doi.org/10.3390/pharmaceutics13050748