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Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors
Recombinant adeno-associated virus (rAAV) vectors have evolved as one of the most promising technologies for gene therapy due to their good safety profile, high transduction efficacy, and long-term gene expression in nondividing cells. rAAV-based gene therapy holds great promise for treating genetic...
Autores principales: | Rieser, Ruth, Koch, Johanna, Faccioli, Greta, Richter, Klaus, Menzen, Tim, Biel, Martin, Winter, Gerhard, Michalakis, Stylianos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158740/ https://www.ncbi.nlm.nih.gov/pubmed/34070226 http://dx.doi.org/10.3390/pharmaceutics13050748 |
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